Autism Research Article Review: Shank3 Mutant Mice Display Autistic-like Behaviours and Striatal Dysfunction

Mouse Shank3 Mutation Creates Autistic-like Behaviors in Mice

Previous research has shown that mutations in the Shank3 gene may play an important role in autism.  This study utilized mouse models to demonstrate that Shank3 mutations resulted in several behaviors characteristic of autism.  Although this is an animal model study it may lead to future studies that provide key insights into the possible connection between the Shank3 gene and autism.  Several … [Read more...]

Autism News: Shank3 Mutation May Hold Clues to Autism

Mutation in Shank3 Gene May Result in Poor Brain Circuitry

Autism News Update: A recent article published on May 20th, 2011 by BBC News reports key findings by scientists at MIT and Duke University.  The scientists created mice with a mutation in the Shank3 gene which encodes a protein found in neuron synapses.  This mutation led to behavior in the mice that mimicked certain autistic behaviors.  The mice in the study showed both repetitive behaviors … [Read more...]