Research for Clonidine as an Autism Treatment:
Clonidine has been studied in the context of controlling hyperactivity and impulsive behaviors in individuals with autism. A case study published in 1994 suggested another use of Catapres (clonidine) as an autism treatment. The doctors describing the case study had seen benefit from prescribing clonidine to control periodic aggressive behaviors in a woman with autism. Their case study was published as a letter to the editor titled Use of Clonidine for Behavioral Control in an Adult Patient with Autism.
The woman had been on several medications to help control her symptoms. Unfortunately, she was still experiencing occasional episodes of severe aggression. Attempts to adjust her medication doses led to increased occurrences of aggression. This led the physicians to initiate clonidine.
Benefits of Clonidine as an Autism Treatment:
The doctors suggest that treatment with clonidine resulted in the following improvements:
- Improved behavior
- Decreased aggressive outbursts
- More alert
- More verbal
The case study also describes an experience when her clonidine patch fell off. They report that this resulted in an episode of increased violence. The authors suggest that other than this experience the patient maintained improved behaviors while on clonidine.
The letter to the editor was published in the American Journal of Psychiatry in November of 1994.
- PubMed Abstract for Use of Clonidine for Behavioral Control in an Adult Patient with Autism
- List of Research for Catapres (Clonidine) Use in Autism
- List of Autism Treatments and Therapies
- More Information about Autism