Autism Environmental Risk Factors: Tylenol (Acetaminophen, Paracetamol)
2012 Research
→Acetaminophen May Mediate Oxidative Stress and Neurotoxicity in Autism
- No research abstract available
2010 Research
→Can Autism Be Triggered by Acetaminophen Activation of the Endocannabinoid System?
- Provides background on research suggesting a link between autism and Tylenol (acetaminophen) use
- Discusses how the mechanism of action of acetaminophen affects the cannabinoid system
- Hypothesizes that acetaminophen use may activate the cannabinoid system resulting in the alteration of normal brain development
→Similarities in Features of Autism and Asthma and a Possible Link to Acetaminophen Use
- Discusses relationship of genes often associated with autism to inflammation and innate immunity pathways
- Describes how asthma is also related to these inflammation and innate immunity pathways
- Discusses how acetaminophen may increase the risk of developing asthma and autism
2009 Research
→Did Acetaminophen Provoke the Autism Epidemic?
- A review article
- Discusses previous research suggesting that autism may be caused by acetaminophen use
- Describes how acetaminophen use may be associated with autism
- Contains section that asks questions arguing against the acetaminophen/autism hypothesis
→A Response to the Article on the Association Between Paracetamol/Acetaminophen: Use and Autism by Stephen T. Schultz
- No summary available
2008 Research
→Acetaminophen (Paracetamol) Use, Measles-Mumps-Rubella Vaccination, and Autistic Disorder: the Results of a Parent Survey
- A case-control study
- Included 163 children (83 with an autism spectrum disorder and 80 neurotypical children)
- Studied the possible association of autism with acetaminophen and ibuprofen use after receiving the MMR vaccine
2003 Research
→Is Fever Suppression Involved in the Etiology of Autism and Neurodevelopmental Disorders?
- A hypothesis paper
- Discusses the use of acetaminophen (paracetamol) by pregnant mothers to treat fevers during pregnancy
- Hypothesizes that acetaminophen use during pregnancy may alter normal brain development
- Provides suggestions for testing the hypothesis and the implications of confirming the hypothesis
Additional Resources:
- More Info About Autism and the Environment
- Additional Information About Autism
