List of Research for Tenex (Guanfacine, Intuniv) for Autism

2010 Research

Possible Influence of Variant of the P-Glycoprotein Gene (MDR1/ABCB1) on Clinical Response to Guanfacine in Children with Pervasive Developmental Disorders and Hyperactivity

  • 8-week, open-label study
  • 25 children with PDD enrolled in the study
  • Focused on the effect of guanfacine on hyperactivity, disruptive behavior, and impulsivity in the context of gene variants in MDR1

2008 Research

Guanfacine in Children with Autism and/or Intellectual Disabilities

  • 6-week double-blind, placebo-controlled crossover study
  • Included 11 children with developmental disabilities and symptoms of inattention/overactivity
  • Focused on the efficacy of guanfacine in treating hyperactivity

2004 Research

Guanfacine Treatment of Hyperactivity and Inattention in Pervasive Developmental Disorders: A Retrospective Analysis of 80 Cases

  • A retrospective, open-label study
  • Included 80 children with pervasive developmental disorders
  • Focused on the efficacy of guanfacine in treating hyperactivity, inattention, and impulsivity
  • Also reported data for insomnia, tics, and side effects


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